The area gathers some of the most important neolithic settlements, not only for the Greek standards but for standards of the Balkan settlements. Until now the archaeological searches have brought in the light around 40 neolithic settlements (7th–8th millennium B.C) and many of them kept being active until 3000 - 1500 B.C the copper era. The most important neolithic settlements are Sesklo and Dimini, where the archeological searches have got to show specific written ceramic work, tools from horn and stone as well as things from volcanic glass, which originate from Milos Island.

           Very important Mycenaic settlements in the area are on the hill of Saint Theodore. Today in Volos this areas are called Palia and Peykakia. At Mycenaic period the establishment of Iolkos is dated one of the most economic and literal center of that time, that is bound with the Myth of the Argonautic expedition. Earlier researchers have though that the place of Iolkos was around the area of Volos called Palia. Newest findings in Dimini contradict the earlier theories and make almost certain, in combination with the written findings that the center of the kings of Iolkos, was in Dimini. There existed the economic center that was based upon agriculture and cattle-breeding, while the economical flourishing, as far as the commerce through the sea was concerned, was performed from the port in Peykakia. During the classical period (6th Century B.C) Pagases flourished which was the seaport of Feres.


           At 293/92 B.C the king of Macedonia Dimitrios the "besieger" has founded the well known town Dimitriada after having settled people at the surrounding large villages. Dimitriada has proven to be one very powerful military station and base of operations for the Macedonians. At the same time has evolved to become an economic centre with peak period of 217-168 B.C. In 197 B.C Dimitriada was occupied by the Romans. The town was built according to the Ipodamius system and was surrounded by very powerful walls. At the eastern part of the town there was the palace, on the southern part there was the market and on the western part there was the theatre (3rd Century B.C). Very important findings of this period are the written script headstones that give interesting clues for the economy, the society and the arts of this period.